Recent Publications

Recent Publications (Newsletter Issue 6)


 

Publications related to CAN-BIND clinical research (published July to October 2018):

 

Early change in reward and punishment sensitivity as a predictor of response to antidepressant treatment for major depressive disorder: a CAN-BIND-1 report

Allen TA, Lam RW, Milev R, Rizvi SJ, Frey BN, MacQueen GM, Müller DJ, Uher R, Kennedy SH, Quilty LC. Early change in reward and punishment sensitivity as a predictor of response to antidepressant treatment for major depressive disorder: a CAN-BIND-1 report. Psychol Med. 2018 Sep 17:1-10. doi: 10.1017/S0033291718002441. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30220263

 

Cortical thickness in major depressive disorder: A systematic review and meta-analysis.

Suh JS, Schneider MA, Minuzzi L, MacQueen GM, Strother SC, Kennedy SH, Frey BN. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Aug 15;88:287-302. doi: 10.1016/j.pnpbp.2018.08.008. [Epub ahead of print] Review. PMID: 30118825

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30118825

 

Metabolic and Microbiota Measures as Peripheral Biomarkers in Major Depressive Disorder.

Horne R, Foster JA. Metabolic and Microbiota Measures as Peripheral Biomarkers in Major Depressive Disorder. Front Psychiatry. 2018 Oct 22;9:513. doi: 10.3389/fpsyt.2018.00513. eCollection 2018.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30405455

 

Youth at-risk for serious mental illness: methods of the PROCAN study.

Addington J, Goldstein BI, Wang JL, Kennedy SH, Bray S, Lebel C, Hassel S, Marshall C, MacQueen G. Youth at-risk for serious mental illness: methods of the PROCAN study.BMC Psychiatry. 2018 Jul 5;18(1):219. doi: 10.1186/s12888-018-1801-0.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29976184

 

Family functioning in youth at-risk for serious mental illness

Santesteban-Echarri O, MacQueen G, Goldstein BI, Wang J, Kennedy SH, Bray S, Lebel C, Addington J. Family functioning in youth at-risk for serious mental illness. Compr Psychiatry. 2018 Aug 25;87:17-24. doi: 10.1016/j.comppsych.2018.08.010. [Epub ahead of print] PMID: 30193153

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30193153

 

Treatment History of Youth At-Risk for Serious Mental Illness

Farris MS, MacQueen G, Goldstein BI, Wang J, Kennedy SH, Bray S, Lebel C, Addington J. Treatment History of Youth At-Risk for Serious Mental Illness. Can J Psychiatry. 2018 Aug 2:706743718792195. doi: 10.1177/0706743718792195. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30071747

 

Neurocognitive deficits in a transdiagnostic clinical staging model

Romanowska S, MacQueen G, Goldstein BI, Wang J, Kennedy SH, Bray S, Lebel C, Addington J. Neurocognitive deficits in a transdiagnostic clinical staging model. Psychiatry Res. 2018 Oct 17. pii: S0165-1781(18)30248-8. doi: 10.1016/j.psychres.2018.10.030. [Epub ahead of print] PMID: 30360915

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30360915

 

Additional Publications involving CAN-BIND Researchers (published July to October 2018):

 

Comparison of the neurocognitive profiles of individuals with elevated psychotic or depressive symptoms.

Grossman M, Best MW, Harrison AG, Bowie CR. Early Interv Psychiatry. Comparison of the neurocognitive profiles of individuals with elevated psychotic or depressive symptoms.2018 Jul 3. doi: 10.1111/eip.12713. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29968389

 

Rhythmicity of Mood Symptoms in Individuals at Risk for Psychiatric Disorders.

Pilz LK, Carissimi A, Oliveira MAB, Francisco AP, Fabris RC, Medeiros MS, Scop M, Frey BN, Adan A, Hidalgo MP. Rhythmicity of Mood Symptoms in Individuals at Risk for Psychiatric Disorders. Sci Rep. 2018 Jul 30;8(1):11402. doi: 10.1038/s41598-018-29348-z.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30061722

 

Executive function in teen and adult women: Association with maternal status and early adversity.

Almanza-Sepulveda ML, Chico E, Gonzalez A, Hall GB, Steiner M, Fleming AS. Executive function in teen and adult women: Association with maternal status and early adversity.Dev Psychobiol. 2018 Jul 24. doi: 10.1002/dev.21766. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30043410

 

Appetitive Symptoms Differentially Predict Treatment Response to Fluoxetine, Light, and Placebo in Nonseasonal Major Depression.

Levitan RD, Levitt AJ, Michalak EE, Morehouse R, Ramasubbu R, Yatham LN, Tam EM, Lam RW. Appetitive Symptoms Differentially Predict Treatment Response to Fluoxetine, Light, and Placebo in Nonseasonal Major Depression.J Clin Psychiatry. 2018 Jul 24;79(4). pii: 17m11856. doi: 10.4088/JCP.17m11856.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30063303

 

Anhedonia in depression and schizophrenia: A transdiagnostic challenge.
Lambert C, Da Silva S, Ceniti AK, Rizvi SJ, Foussias G, Kennedy SH. Anhedonia in depression and schizophrenia: A transdiagnostic challenge.CNS Neurosci Ther. 2018 Jul;24(7):615-623. doi: 10.1111/cns.12854. Epub 2018 Apr 23. Review.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29687627

 

Association between irritability and suicide-related outcomes across the life-course. Systematic review of both community and clinical studies.

Orri M, Perret LC, Turecki G, Geoffroy MC. Association between irritability and suicide-related outcomes across the life-course. Systematic review of both community and clinical studies. J Affect Disord. 2018 Oct 15;239:220-233. doi: 10.1016/j.jad.2018.07.010. Epub 2018 Jul 4. Review.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30025311

 

Stability, reliability, and validity of the THINC-it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers.

Harrison JE, Barry H, Baune BT, Best MW, Bowie CR, Cha DS, Culpepper L, Fossati P, Greer TL, Harmer C, Klag E, Lam RW, Lee Y, Mansur RB, Wittchen HU, McIntyre RS. Stability, reliability, and validity of the THINC-it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers. Int J Methods Psychiatr Res. 2018 Sep;27(3):e1736. doi: 10.1002/mpr.1736. Epub 2018 Aug 7. PMID: 30088298

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30088298

 

The Role of Circadian Rhythms in Postpartum Sleep and Mood

Gallaher KGH, Slyepchenko A, Frey BN, Urstad K, Dørheim SK. The Role of Circadian Rhythms in Postpartum Sleep and Mood. Sleep Med Clin. 2018 Sep;13(3):359-374. doi: 10.1016/j.jsmc.2018.04.006. Review. PMID: 30098753

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30098753

 

Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial

Ott CV, Vinberg M, Bowie CR, Christensen EM, Knudsen GM, Kessing LV, Miskowiak KW. Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial. Trials. 2018 Sep 12;19(1):487. doi: 10.1186/s13063-018-2860-8.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30208971

 

Evidence for the Efficacy of Bright Light Therapy for Bipolar Depression

Benedetti F1, Avery DH1, Bauer M1, Bunney WE1, Çaliyurt O1, Camardese G1, Colombo C1, Dallaspezia S1, Henriksen TE1, Kasper S1, Kuriyama K1, Lam RW1, Martiny K1, Meesters Y1, Mishima K1, Schulte R1, Suzuki M1, Święcicki Ł1, Uchiyama M1, Veale D1, Winkler D1, Wu J1, Kupeli NY1, Yoshiike T1, Yu X1. Evidence for the Efficacy of Bright Light Therapy for Bipolar Depression. Am J Psychiatry. 2018 Sep 1;175(9):905-906. doi: 10.1176/appi.ajp.2018.18020231.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30173556

 

Abuse as a risk factor for prenatal depressive symptoms: a meta-analysis

Shamblaw AL, Cardy RE, Prost E, Harkness KL. Abuse as a risk factor for prenatal depressive symptoms: a meta-analysis. Arch Womens Ment Health. 2018 Sep 8. doi: 10.1007/s00737-018-0900-8. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30196369

 

Internet use by older adults with bipolar disorder: international survey results

Bauer R, Glenn T, Strejilevich S, Conell J, Alda M, Ardau R, Baune BT, Berk M, Bersudsky Y, Bilderbeck A, Bocchetta A, Castro AMP, Cheung EYW, Chillotti C, Choppin S, Cuomo A, Del Zompo M, Dias R, Dodd S, Duffy A, Etain B, Fagiolini A, Fernández Hernandez M, Garnham J, Geddes J, Gildebro J, Gitlin MJ, Gonzalez-Pinto A, Goodwin GM, Grof P, Harima H, Hassel S, Henry C, Hidalgo-Mazzei D, Lund AH, Kapur V, Kunigiri G, Lafer B, Larsen ER, Lewitzka U, Licht RW, Misiak B, Piotrowski P, Miranda-Scippa Â, Monteith S, Munoz R, Nakanotani T, Nielsen RE, O’Donovan C, Okamura Y, Osher Y, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Sawchuk B, Schwartz E, Slaney C, Sulaiman AH, Suominen K, Suwalska A, Tam P, Tatebayashi Y, Tondo L, Veeh J, Vieta E, Vinberg M, Viswanath B, Zetin M, Whybrow PC, Bauer M. Internet use by older adults with bipolar disorder: international survey results. Int J Bipolar Disord. 2018 Sep 4;6(1):20. doi: 10.1186/s40345-018-0127-7.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30178112

 

Examining suicide-related presentations to the emergency department

Ceniti AK, Heinecke N, McInerney SJ. Examining suicide-related presentations to the emergency department. Gen Hosp Psychiatry. 2018 Sep 18. pii: S0163-8343(18)30072-0. doi: 10.1016/j.genhosppsych.2018.09.006. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30268506

 

Guidelines for the Evaluation and Treatment of Perimenopausal Depression: Summary and Recommendations

Maki PM, Kornstein SG, Joffe H, Bromberger JT, Freeman EW, Athappilly G, Bobo WV, Rubin LH, Koleva HK, Cohen LS, Soares CN. Guidelines for the Evaluation and Treatment of Perimenopausal Depression: Summary and Recommendations. J Womens Health (Larchmt). 2018 Sep 5. doi: 10.1089/jwh.2018.27099.mensocrec. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30182804

 

Comparative study of esketamine and racemic ketamine in treatment-resistant depression: Protocol for a non-inferiority clinical trial

Correia-Melo FS, Leal GC, Carvalho MS, Jesus-Nunes AP, Ferreira CBN, Vieira F, Magnavita G, Vale LAS, Mello RP, Nakahira C, Argolo FC, Cardoso T, Souza CDS, Fontes ATC, Ferreira MB, Araújo-de-Freitas L, Tuena MA, Echegaray MVF, Cavalcanti DE, Lucchese AC, Bandeira ID, Telles M, Lima CS, Sampaio AS, Silva SS, Marback RF, Del-Porto JA, Abreu JN, Sarin LM, Paixão CS, Carvalho LP, Machado PRL, Turecki G, Lacerda ALT, Quarantini LC. Comparative study of esketamine and racemic ketamine in treatment-resistant depression: Protocol for a non-inferiority clinical trial. Medicine (Baltimore). 2018 Sep;97(38):e12414. doi: 10.1097/MD.0000000000012414.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30235716

 

Attention-deficit hyperactivity disorder and anxiety disorders as precursors of bipolar disorder onset in adulthood

Meier SM, Pavlova B, Dalsgaard S, Nordentoft M, Mors O, Mortensen PB, Uher R. Attention-deficit hyperactivity disorder and anxiety disorders as precursors of bipolar disorder onset in adulthood. Br J Psychiatry. 2018 Sep;213(3):555-560. doi: 10.1192/bjp.2018.111. Epub 2018 Jun 21.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29925436. 

 

Effect of agomelatine 25-50 mg on functional outcomes in patients with major depressive disorder.

Kennedy SH, Heun R, Avedisova A, Ahokas A, Olivier V, Picarel-Blanchot F, de Bodinat C. Effect of agomelatine 25-50 mg on functional outcomes in patients with major depressive disorder. J Affect Disord. 2018 Oct 1;238:122-128. doi: 10.1016/j.jad.2018.05.060. Epub 2018 May 29.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29879606

 

Family cohesion and flexibility in early episode psychosis

Gupta M, Bowie CR. Family cohesion and flexibility in early episode psychosis. Early Interv Psychiatry. 2018 Oct;12(5):886-892. doi: 10.1111/eip.12384. Epub 2016 Sep 7.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27601077

 

Revising Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, criteria for the bipolar disorders: Phase I of the AREDOC project.

Parker G, Tavella G, Macqueen G, Berk M, Grunze H, Deckersbach T, Dunner DL, Sajatovic M, Amsterdam JD, Ketter TA, Yatham LN, Kessing LV, Bassett D, Zimmerman M, Fountoulakis KN,

Duffy A, Alda M, Calkin C, Sharma V, Anand A, Singh MK, Hajek T, Boyce P, Frey BN, Castle DJ, Young AH, Vieta E, Rybakowski JK, Swartz HA, Schaffer A, Murray G, Bayes A, Lam RW, Bora E, Post RM, Ostacher MJ, Lafer B, Cleare AJ, Burdick KE, O’Donovan C, Ortiz A, Henry C, Kanba S, Rosenblat JD, Parikh SV, Bond DJ, Grunebaum MF, Frangou S, Goldberg JF, Orum M, Osser DN, Frye MA, McIntyre RS, Fagiolini A, Manicavasagar V, Carlson GA, Malhi GS. Revising Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, criteria for the bipolar disorders: Phase I of the AREDOC project. Aust N Z J Psychiatry. 2018 Oct 31:4867418808382. doi: 10.1177/0004867418808382. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30378461

 

Risk factors of new onset anxiety and anxiety exacerbation in the perinatal period: A systematic review and meta-analysis.

Furtado M, Chow CHT, Owais S, Frey BN, Van Lieshout RJ. Risk factors of new onset anxiety and anxiety exacerbation in the perinatal period: A systematic review and meta-analysis. J Affect Disord. 2018 Oct 1;238:626-635. doi: 10.1016/j.jad.2018.05.073. Epub 2018 Jun 18. Review. PMID: 29957480

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29957480

 

Non-pharmacological interventions for improving postpartum maternal sleep: A systematic review and meta-analysis.

Owais S, Chow CHT, Furtado M, Frey BN, Van Lieshout RJ. Non-pharmacological interventions for improving postpartum maternal sleep: A systematic review and meta-analysis. Sleep Med Rev. 2018 Oct;41:87-100. doi: 10.1016/j.smrv.2018.01.005. Epub 2018 Jan 31. Review. PMID: 29449122

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29449122

 

Childhood emotional abuse, physical abuse, and neglect are associated with theory of mind decoding accuracy in young adults with depression.

Rnic K, Sabbagh MA, Washburn D, Bagby RM, Ravindran A, Kennedy JL, Strauss J, Harkness KL. Childhood emotional abuse, physical abuse, and neglect are associated with theory of mind decoding accuracy in young adults with depression. Psychiatry Res. 2018 Oct;268:501-507. doi: 10.1016/j.psychres.2018.07.045. Epub 2018 Aug 2.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30165325

 

The association of duration and severity of disease with executive function: Differences between drug-naïve patients with bipolar and unipolar depression.

Yang T, Zhao G, Mao R, Huang J, Xu X, Su Y, Zhu N, Zhou R, Lin X, Xia W, Wang F, Liu R, Wang X, Huang Z, Wang Y, Hu Y, Cao L, Yuan C, Wang Z, Lam RW, Chen J, Fang Y. The association of duration and severity of disease with executive function: Differences between drug-naïve patients with bipolar and unipolar depression. J Affect Disord. 2018 Oct 1;238:412-417. doi: 10.1016/j.jad.2018.05.051. Epub 2018 May 29.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29909305

 

Toward Effective Work Accommodations for Depression: Examining the Relationship between Different Combinations of Depression Symptoms and Work Productivity Losses.

Dewa CS, Hoch JS, Nieuwenhuijsen K, Parikh SV, Sluiter JK. Toward Effective Work Accommodations for Depression: Examining the Relationship between Different Combinations of Depression Symptoms and Work Productivity Losses. J Occup Environ Med. 2018 Oct 22. doi: 10.1097/JOM.0000000000001486. [Epub ahead of print] PMID: 30358657

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30358657

 

Association Between Catastrophizing and Dizziness-Related Disability Assessed With the Dizziness Catastrophizing Scale.

Pothier DD, Shah P, Quilty L, Ozzoude M, Dillon WA, Rutka JA, Gerretsen P. Association Between Catastrophizing and Dizziness-Related Disability Assessed With the Dizziness Catastrophizing Scale. JAMA Otolaryngol Head Neck Surg. 2018 Oct 1;144(10):906-912. doi: 10.1001/jamaoto.2018.1863.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30128545

 

Guidelines for the evaluation and treatment of perimenopausal depression: summary and recommendations.

Maki PM, Kornstein SG, Joffe H, Bromberger JT, Freeman EW, Athappilly G, Bobo WV, Rubin LH, Koleva HK, Cohen LS, Soares CN; Board of Trustees for The North American Menopause Society (NAMS) and the Women and Mood Disorders Task Force of the National Network of Depression Centers. Guidelines for the evaluation and treatment of perimenopausal depression: summary and recommendations. Menopause. 2018 Oct;25(10):1069-1085. doi: 10.1097/GME.0000000000001174.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30179986

 

A visual analog scale to measure psychological and physical pain: A preliminary validation of the PPP-VAS in two independent samples of depressed patients.

Jollant F, Voegeli G, Kordsmeier NC, Carbajal JM, Richard-Devantoy S, Turecki G, Cáceda R. A visual analog scale to measure psychological and physical pain: A preliminary validation of the PPP-VAS in two independent samples of depressed patients. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Oct 31. pii: S0278-5846(18)30383-X. doi: 10.1016/j.pnpbp.2018.10.018. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30391308

 

Association between irritability and suicide-related outcomes across the life-course. Systematic review of both community and clinical studies.

Orri M, Perret LC, Turecki G, Geoffroy MC. Association between irritability and suicide-related outcomes across the life-course. Systematic review of both community and clinical studies. J Affect Disord. 2018 Oct 15;239:220-233. doi: 10.1016/j.jad.2018.07.010. Epub 2018 Jul 4. Review. PMID: 30025311

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30025311

 

Protocol for the development of a CONSORT extension for RCTs using cohorts and routinely collected health data.

Kwakkenbos L, Juszczak E, Hemkens LG, Sampson M, Fröbert O, Relton C, Gale C, Zwarenstein M, Langan SM, Moher D, Boutron I, Ravaud P, Campbell MK, Mc Cord KA, van Staa TP, Thabane L, Uher R, Verkooijen HM, Benchimol EI, Erlinge D, Sauvé M, Torgerson D, Thombs BD. Protocol for the development of a CONSORT extension for RCTs using cohorts and routinely collected health data. Res Integr Peer Rev. 2018 Oct 29;3:9. doi: 10.1186/s41073-018-0053-3. eCollection 2018.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30397513

 

Cortical Volume and Thickness Across Bipolar Disorder Subtypes in Adolescents: A Preliminary Study.

Toma S, Islam AH, Metcalfe AWS, Mitchell RHB, Fiksenbaum L, MacIntosh BJ, Goldstein BI. J Child Cortical Volume and Thickness Across Bipolar Disorder Subtypes in Adolescents: A Preliminary Study. Adolesc Psychopharmacol. 2018 Oct 25. doi: 10.1089/cap.2017.0137. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30359542

 

A Risk Calculator to Predict the Individual Risk of Conversion From Subthreshold Bipolar Symptoms to Bipolar Disorder I or II in Youth.

Birmaher B, Merranko JA, Goldstein TR, Gill MK, Goldstein BI, Hower H, Yen S, Hafeman D, Strober M, Diler RS, Axelson D, Ryan ND, Keller MB. A Risk Calculator to Predict the Individual Risk of Conversion From Subthreshold Bipolar Symptoms to Bipolar Disorder I or II in Youth. J Am Acad Child Adolesc Psychiatry. 2018 Oct;57(10):755-763.e4. doi: 10.1016/j.jaac.2018.05.023. Epub 2018 Aug 7.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30274650

 

Mouse MRI shows brain areas relatively larger in males emerge before those larger in females.

Qiu LR, Fernandes DJ, Szulc-Lerch KU, Dazai J, Nieman BJ, Turnbull DH, Foster JA, Palmert MR, Lerch JP. Mouse MRI shows brain areas relatively larger in males emerge before those larger in females. Nat Commun. 2018 Jul 5;9(1):2615. doi: 10.1038/s41467-018-04921-2.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29976930

 

Magnetic resonance imaging evidence of hippocampal structural changes in patients with primary biliary cholangitis.

Mosher VAL, Swain MG, Pang JXQ, Kaplan GG, Sharkey KA, MacQueen GM, Goodyear BG. Magnetic resonance imaging evidence of hippocampal structural changes in patients with primary biliary cholangitis.Clin Transl Gastroenterol. 2018 Jul 6;9(7):169. doi: 10.1038/s41424-018-0038-z.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29977030

 

Resting state functional connectivity in patients with remitted psychotic depression: A multi-centre STOP-PD study.

Neufeld NH, Mulsant BH, Dickie EW, Meyers BS, Alexopoulos GS, Rothschild AJ, Whyte EM, Hoptman MJ, Nazeri A, Downar J, Flint AJ, Voineskos AN. Resting state functional connectivity in patients with remitted psychotic depression: A multi-centre STOP-PD study. EBioMedicine. 2018 Oct;36:446-453. doi: 10.1016/j.ebiom.2018.09.025. Epub 2018 Oct 1.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30287158

 

FDG PET Parkinson’s disease-related pattern as a biomarker for clinical trials in early stage disease.

Matthews DC, Lerman H, Lukic A, Andrews RD, Mirelman A, Wernick MN, Giladi N, Strother SC, Evans KC, Cedarbaum JM, Even-Sapir E. FDG PET Parkinson’s disease-related pattern as a biomarker for clinical trials in early stage disease. Neuroimage Clin. 2018 Aug 10;20:572-579. doi: 10.1016/j.nicl.2018.08.006. eCollection 2018. PMID: 30186761

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30186761

 

An Emotional Go/No-Go fMRI study in adolescents with depressive symptoms following concussion.

Ho RA, Hall GB, Noseworthy MD, DeMatteo C. An Emotional Go/No-Go fMRI study in adolescents with depressive symptoms following concussion. Int J Psychophysiol. 2018 Oct;132(Pt A):62-73. doi: 10.1016/j.ijpsycho.2017.09.021. Epub 2017 Oct 3.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28986325

 

The role of neuronal nitric oxide synthase in cocaine place preference and mu opioid receptor expression in the nucleus accumbens

Thériault RK, Leri F, Kalisch B. The role of neuronal nitric oxide synthase in cocaine place preference and mu opioid receptor expression in the nucleus accumbens. Psychopharmacology (Berl).
2018 Sep;235(9):2675-2685. doi: 10.1007/s00213-018-4961-1. Epub 2018 Jul 10.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29992335

 

Involvement of 5-HT1A and 5-HT2A Receptors but Not α 2-Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo.

Herman A, El Mansari M, Adham N, Kiss B, Farkas B, Blier P. Involvement of 5-HT1A and 5-HT2A Receptors but Not α 2-Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo. Mol Pharmacol. 2018 Dec;94(6):1363-1370. doi: 10.1124/mol.118.113290. Epub 2018 Oct 15.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30322874

 

Pharmacogenetic evaluation of a DISP1 gene variant in antidepressant treatment of obsessive-compulsive disorder.

Lisoway AJ, Zai G, Tiwari AK, Zai CC, Wigg K, Goncalves V, Zhang D, Freeman N, Müller DJ, Kennedy JL, Richter MA. Pharmacogenetic evaluation of a DISP1 gene variant in antidepressant treatment of obsessive-compulsive disorder. Hum Psychopharmacol. 2018 Jul;33(4):e2659. doi: 10.1002/hup.2659. Epub 2018 Jun 28.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29953682

 

Evidence of Reduced Agmatine Concentrations in the Cerebral Cortex of Suicides.

Chen GG, Almeida D, Fiori L, Turecki G. Evidence of Reduced Agmatine Concentrations in the Cerebral Cortex of Suicides. Int J Neuropsychopharmacol. 2018 Oct 1;21(10):895-900. doi: 10.1093/ijnp/pyy058.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29986038

 

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study.

Erlangsen A, Appadurai V, Wang Y, Turecki G, Mors O, Werge T, Mortensen PB, Starnawska A, Børglum AD, Schork A, Nudel R, Bækvad-Hansen M, Bybjerg-Grauholm J, Hougaard DM, Thompson WK, Nordentoft M, Agerbo E. Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study.Mol Psychiatry. 2018 Aug 16. doi: 10.1038/s41380-018-0218-y. [Epub ahead of print] PMID: 30116032

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30116032

 

EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia.

Johnstone AL, O’Reilly JJ, Patel AJ, Guo Z, Andrade NS, Magistri M, Nathanson L, Esanov R, Miller BH, Turecki G, Brothers SP, Zeier Z, Wahlestedt C. EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia. Neurobiol Dis. 2018 Nov;119:149-158. doi: 10.1016/j.nbd.2018.08.005. Epub 2018 Aug 9. PMID: 30099093

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30099093

 

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies.

Fabbri C, Tansey KE, Perlis RH, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Breen G, Curtis C, Lee SH, Newhouse S, Patel H, O’Donovan M, Lewis G, Jenkins G, Weinshilboum RM, Farmer A, Aitchison KJ, Craig I, McGuffin P, Schruers K, Biernacka JM, Uher R, Lewis CM. Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies. Eur Neuropsychopharmacol. 2018 Aug;28(8):945-954. doi: 10.1016/j.euroneuro.2018.05.009. Epub 2018 Jun 28. PMID: 30135031

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30135031

 

Genetic disposition to inflammation and response to antidepressants in major depressive disorder.

Zwicker A, Fabbri C, Rietschel M, Hauser J, Mors O, Maier W, Zobel A, Farmer A, Aitchison KJ, McGuffin P, Lewis CM, Uher R. Genetic disposition to inflammation and response to antidepressants in major depressive disorder. J Psychiatr Res. 2018 Oct;105:17-22. doi: 10.1016/j.jpsychires.2018.08.011. Epub 2018 Aug 7.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30130674

 

Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP).

Ren H, Fabbri C, Uher R, Rietschel M, Mors O, Henigsberg N, Hauser J, Zobel A, Maier W, Dernovsek MZ, Souery D, Cattaneo A, Breen G, Craig IW, Farmer AE, McGuffin P, Lewis CM, Aitchison KJ. Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP). Transl Psychiatry. 2018 Aug 13;8(1):150. doi: 10.1038/s41398-018-0198-3.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30104601

 

A dual noradrenergic mechanism for the relief of neuropathic allodynia by the antidepressant drugs duloxetine and amitriptyline

Kremer M, Yalcin I, Goumon Y, Wurtz X, Nexon L, Daniel D, Megat S, Ceredig RA, Ernst C, Turecki G, Chavant V, Theroux JF, Lacaud A, Joganah LE, Lelievre V, Massotte D, Lutz PE, Gilsbach R, Salvat E, Barrot M. A dual noradrenergic mechanism for the relief of neuropathic allodynia by the antidepressant drugs duloxetine and amitriptyline. J Neurosci. 2018 Sep 24. pii: 1004-18. doi: 10.1523/JNEUROSCI.1004-18.2018. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30249798

 

Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples

Aberg KA, Dean B, Shabalin AA, Chan RF, Han LKM, Zhao M, van Grootheest G, Xie LY, Milaneschi Y, Clark SL, Turecki G, Penninx BWJH, van den Oord EJCG. Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples. Mol Psychiatry. 2018 Sep 21. doi: 10.1038/s41380-018-0247-6. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30242228

 

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts

Ward J, Graham N, Strawbridge RJ, Ferguson A, Jenkins G, Chen W, Hodgson K, Frye M, Weinshilboum R3, Uher R, Lewis CM, Biernacka J, Smith DJ. Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts. PLoS One. 2018 Sep 21;13(9):e0203896. doi: 10.1371/journal.pone.0203896. eCollection 2018.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30240446

 

Gene-environment interplay in the etiology of psychosis

Zwicker A, Denovan-Wright EM, Uher R. Gene-environment interplay in the etiology of psychosis. Psychol Med. 2018 Sep;48(12):1925-1936. doi: 10.1017/S003329171700383X. Epub 2018 Jan 15.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29334044 

 

Global long non-coding RNA expression in the rostral anterior cingulate cortex of depressed suicides.

Zhou Y, Lutz PE, Wang YC, Ragoussis J, Turecki G. Global long non-coding RNA expression in the rostral anterior cingulate cortex of depressed suicides. Transl Psychiatry. 2018 Oct 18;8(1):224. doi: 10.1038/s41398-018-0267-7. PMID: 30337518

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30337518

 

Accelerated Magnetic Seizure Therapy for Treatment of Major Depressive Disorder: A Report of 3 Cases.

Wang J, Vila-Rodriguez F, Jiang W, Ren YP, Wang CM, Ma X. Accelerated Magnetic Seizure Therapy for Treatment of Major Depressive Disorder: A Report of 3 Cases. J ECT. 2018 Jul 3. doi: 10.1097/YCT.0000000000000521. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29979250

 

Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation.

Leoutsakos JS, Yan H, Anderson WS, Asaad WF, Baltuch G, Burke A, Chakravarty MM, Drake KE, Foote KD, Fosdick L, Giacobbe P, Mari Z, McAndrews MP, Munro CA, Oh ES, Okun MS, Pendergrass JC, Ponce FA, Rosenberg PB, Sabbagh MN, Salloway S, Tang-Wai DF, Targum SD, Wolk D, Lozano AM, Smith GS, Lyketsos CG. Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation. J Alzheimers Dis. 2018;64(2):597-606. doi: 10.3233/JAD-180121.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29914028

 

A Case for the Frontal Pole as an Empirically Derived Neuromodulation Treatment Target.

Hanlon CA, Philip NS, Price RB, Bickel WK, Downar J. Biol Psychiatry. A Case for the Frontal Pole as an Empirically Derived Neuromodulation Treatment Target.2018 Aug 17. pii: S0006-3223(18)31666-4. doi: 10.1016/j.biopsych.2018.07.002. [Epub ahead of print] No abstract available.
PMID: 30126608

 

Characteristics of ictal EEG in Magnetic Seizure Therapy at various stimulation frequencies.

Backhouse FA, Noda Y, Knyahnytska Y, Farzan F, Downar J, Rajji TK, Mulsant BH, Daskalakis ZJ, Blumberger DM. Characteristics of ictal EEG in Magnetic Seizure Therapy at various stimulation frequencies. Clin Neurophysiol. 2018 Aug;129(8):1770-1779. doi: 10.1016/j.clinph.2018.03.025. Epub 2018 Apr 22.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29735419

 

Development and validation of a 3D-printed neuronavigation headset for therapeutic brain stimulation.

Mansouri F, Mir-Moghtadaei A, Niranjan V, Wu JS, Akhmedjanov D, Nuh M, Cairo T, Giacobbe P, Zariffa J, Downar J. Development and validation of a 3D-printed neuronavigation headset for therapeutic brain stimulation.  J Neural Eng. 2018 Aug;15(4):046034. doi: 10.1088/1741-2552/aacb96. Epub 2018 Jun 11.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29888708

 

Efficacy, tolerability, and cognitive effects of deep transcranial magnetic stimulation for late-life depression: a prospective randomized controlled trial.

Kaster TS, Daskalakis ZJ, Noda Y, Knyahnytska Y, Downar J, Rajji TK, Levkovitz Y, Zangen A, Butters MA, Mulsant BH, Blumberger DM. Efficacy, tolerability, and cognitive effects of deep transcranial magnetic stimulation for late-life depression: a prospective randomized controlled trial. Neuropsychopharmacology. 2018 Oct;43(11):2231-2238. doi: 10.1038/s41386-018-0121-x. Epub 2018 Jun 18.

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29946106

 

Selective modulation of brain network dynamics by seizure therapy in treatment-resistant depression.

Atluri S, Wong W, Moreno S, Blumberger DM, Daskalakis ZJ, Farzan F. Selective modulation of brain network dynamics by seizure therapy in treatment-resistant depression. Neuroimage Clin. 2018 Oct 17;20:1176-1190. doi: 10.1016/j.nicl.2018.10.015. [Epub ahead of print]

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30388600