Publications
- 2023
Ballester, P. L., Suh, J. S., Ho, N. C. W., Liang, L., Hassel, S., Strother, S. C., Arnott, S. R., Minuzzi, L., Sassi, R. B., Lam, R. W., Milev, R., Müller, D. J., Taylor, V. H., Kennedy, S. H., Reilly, J. P., Palaniyappan, L., Dunlop, K., & Frey, B. N. (2023). Gray matter volume drives the brain age gap in schizophrenia: A SHAP study. Schizophrenia, 9(1), 3. https://doi.org/10.1038/s41537-022-00330-z
Dama, M., Wu, M., Tassone, V. K., Demchenko, I., Frey, B. N., Milev, R. V., Ravindran, A. V., Parikh, S. V., Rotzinger, S., Lou, W., Lam, R. W., Kennedy, S. H., & Bhat, V. (2023). The course of insomnia symptoms during the acute treatment of major depressive disorder: A CAN-BIND-1 report. Psychiatry Research, 325, 115222. https://doi.org/10.1016/j.psychres.2023.115222
Fu, C. H. Y., Erus, G., Fan, Y., Antoniades, M., Arnone, D., Arnott, S. R., Chen, T., Choi, K. S., Fatt, C. C., Frey, B. N., Frokjaer, V. G., Ganz, M., Garcia, J., Godlewska, B. R., Hassel, S., Ho, K., McIntosh, A. M., Qin, K., Rotzinger, S., … Davatzikos, C. (2023). AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale. BMC Psychiatry, 23(1), 59. https://doi.org/10.1186/s12888-022-04509-7
Harkness, K. L., Chakrabarty, T., Rizvi, S. J., Mazurka, R., Quilty, L., Uher, R., Milev, R. V., Frey, B. N., Parikh, S. V., Foster, J. A., Rotzinger, S., Kennedy, S. H., & Lam, R. W. (2023). The differential relation of emotional, physical, and sexual abuse histories to antidepressant treatment remission and persistence of anhedonia in major depression: A can-bind-1 report. The Canadian Journal of Psychiatry, 68(8), 586–595. https://doi.org/10.1177/07067437231156255
Islam, F., Marshe, V. S., Magarbeh, L., Frey, B. N., Milev, R. V., Soares, C. N., Parikh, S. V., Placenza, F., Strother, S. C., Hassel, S., Taylor, V. H., Leri, F., Blier, P., Uher, R., Farzan, F., Lam, R. W., Turecki, G., Foster, J. A., Rotzinger, S., … Müller, D. J. (2022). Effects of CYP2C19 and CYP2D6 gene variants on escitalopram and aripiprazole treatment outcome and serum levels: Results from the CAN-BIND 1 study. Translational Psychiatry, 12(1), 366. https://doi.org/10.1038/s41398-022-02124-4
Magarbeh, L., Hassel, C., Choi, M., Islam, F., Marshe, V. S., Zai, C. C., Zuberi, R., Gammal, R. S., Men, X., Scherf‐Clavel, M., Enko, D., Frey, B. N., Milev, R., Soares, C. N., Parikh, S. V., Placenza, F., Strother, S. C., Hassel, S., Taylor, V. H., … Müller, D. J. (2023). abcb1 gene variants and antidepressant treatment outcomes: A systematic review and meta‐analysis including results from the CAN-BIND 1 study. Clinical Pharmacology & Therapeutics, 114(1), 88–117. https://doi.org/10.1002/cpt.2854
Melanson, B., Wolter, M., Leatham, Z., Lapointe, T., Kennedy, S., & Leri, F. (2023). Conditioned anti-immobility by ketamine: A comparison to escitalopram and bupropion. Experimental and Clinical Psychopharmacology, 31(2), 350–361. https://doi.org/10.1037/pha0000573
Sajjadian, M., Lam, R. W., Milev, R., Rotzinger, S., Frey, B. N., Soares, C. N., Parikh, S. V., Foster, J. A., Turecki, G., Müller, D. J., Strother, S. C., Farzan, F., Kennedy, S. H., & Uher, R. (2021). Machine learning in the prediction of depression treatment outcomes: A systematic review and meta-analysis. Psychological Medicine, 51(16), 2742–2751. https://doi.org/10.1017/S0033291721003871
Dikaios, K., Rempel, S., Dumpala, S. H., Oore, S., Kiefte, M., & Uher, R. (2023). Applications of speech analysis in psychiatry. Harvard Review of Psychiatry, 31(1), 1–13. https://doi.org/10.1097/HRP.0000000000000356
- 2022
Sajjadian, M., Uher, R., Ho, K., Hassel, S., Milev, R., Frey, B. N., Farzan, F., Blier, P., Foster, J. A., Parikh, S. V., Müller, D. J., Rotzinger, S., Soares, C. N., Turecki, G., Taylor, V. H., Lam, R. W., Strother, S. C., & Kennedy, S. H. (2022). Prediction of depression treatment outcome from multimodal data: a CAN-BIND-1 report. Psychological medicine, 1–11. Advance online publication. https://doi.org/10.1017/S0033291722002124
Ceniti, A. K., Abdelmoemin, W. R., Ho, K., Kang, Y., Placenza, F., Laframboise, R., … & Kennedy, S. H. (2022). “One Degree of Separation”: A Mixed-Methods Evaluation of Canadian Mental Health Care User and Provider Experiences With Remote Care During COVID-19. The Canadian Journal of Psychiatry, 07067437211070656.
Dhami, P., Quilty, L. C., Schwartzmann, B., Uher, R., Allen, T. A., Kloiber, S., … & Farzan, F. (2022). Response Inhibition and Predicting Response to Pharmacological and Cognitive Behavioral Therapy Treatments for Major Depressive Disorder: A CAN-BIND Study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
Espinola, C. W., Khoo, Y., Parmar, R., Demchenko, I., Frey, B. N., Milev, R. V., … & CAN‐BIND Investigator Team. (2022). Pretreatment anxious depression as a predictor of side effect frequency and severity in escitalopram and aripiprazole adjunctive therapy. Brain and Behavior, e2555.
Nogovitsyn, N., Metzak, P. D., Casseb, R. F., Souza, R., Harris, J. K., Prati, L. M., … & Addington, J. (2022). Cerebello-limbic functional connectivity patterns in youth at clinical high risk for psychosis. Schizophrenia Research, 240, 220-227.
Vaccarino, A. L., Beaton, D., Black, S. E., Blier, P., Farzan, F., Finger, E., … & Evans, K. R. (2022). Common Data Elements to Facilitate Sharing and Re-use of Participant-Level Data: Assessment of Psychiatric Comorbidity Across Brain Disorders. Frontiers in psychiatry, 65.
Espinola, C. W., Khoo, Y., Parmar, R., Demchenko, I., Frey, B. N., Milev, R. V., Ravindran, A. V., Parikh, S. V., Ho, K., Rotzinger, S., Lou, W., Lam, R. W., Kennedy, S. H., & Bhat, V. (2022). Males and females differ in reported sexual functioning with escitalopram treatment for major depressive disorder: A CAN-BIND-1 study report. Journal of psychopharmacology (Oxford, England), 36(5), 604–613. https://doi.org/10.1177/02698811221095832
Khoo, Y., Demchenko, I., Frey, B. N., Milev, R. V., Ravindran, A. V., Parikh, S. V., Ho, K., Rotzinger, S., Lou, W., Lam, R. W., Kennedy, S. H., Bhat, V., & CAN-BIND Investigator Team (2022). Baseline anxiety, and early anxiety/depression improvement in anxious depression predicts treatment outcomes with escitalopram: A CAN-BIND-1 study report. Journal of affective disorders, 300, 50–58. https://doi.org/10.1016/j.jad.2021.12.027
Dama, M., Khoo, Y., Frey, B. N., Milev, R. V., Ravindran, A. V., Parikh, S. V., … & Team, C. B. I. (2022). Rhythmicity of sleep and clinical outcomes in major depressive disorder: A CAN-BIND-1 Report. Journal of Affective Disorders Reports, 100370.
Harris, J. K., Hassel, S., Davis, A. D., Zamyadi, M., Arnott, S. R., Milev, R., Lam, R. W., Frey, B. N., Hall, G. B., Müller, D. J., Rotzinger, S., Kennedy, S. H., Strother, S. C., MacQueen, G. M., & Greiner, R. (2022). Predicting escitalopram treatment response from pre-treatment and early response resting state fMRI in a multi-site sample: A CAN-BIND-1 report. NeuroImage. Clinical, 35, 103120. https://doi.org/10.1016/j.nicl.2022.103120
Hicks, O., McInerney, S. J., Lam, R. W., Milev, R. V., Frey, B. N., Soares, C. N., Foster, J. A., Rotzinger, S., Kennedy, S. H., & Harkness, K. L. (2022). Acute and chronic stress predict anti-depressant treatment outcome and naturalistic course of major depression: A CAN-BIND report. Journal of affective disorders, 313, 8–14. https://doi.org/10.1016/j.jad.2022.06.058
- 2021
Allen, T. A., Harkness, K. L., Lam, R. W., Milev, R., Frey, B. N., Mueller, D. J., … & Quilty, L. C. (2021). Interactions between neuroticism and stressful life events predict response to pharmacotherapy for major depression: A CAN‐BIND 1 report. Personality and Mental Health, 15(4), 273-282.
Anteraper, S. A., Guell, X., Lee, Y. J., Raya, J., Demchenko, I., Churchill, N. W., … & Bhat, V. (2022). Cerebello-cerebral Functional Connectivity Networks in Major Depressive Disorder: A CAN-BIND-1 Study Report. The Cerebellum, 1-11.
Ayyash, S., Davis, A. D., Alders, G. L., MacQueen, G., Strother, S. C., Hassel, S., … & CAN‐BIND Investigator Team. (2021). Exploring brain connectivity changes in major depressive disorder using functional‐structural data fusion: A CAN‐BIND‐1 study. Human brain mapping.
Ballester, P. L., Romano, M. T., de Azevedo Cardoso, T., Hassel, S., Strother, S. C., Kennedy, S. H., & Frey, B. N. (2021). Brain age in mood and psychotic disorders: a systematic review and meta‐analysis. Acta Psychiatrica Scandinavica.
Ballester, P. L., Suh, J. S., Nogovitsyn, N., Hassel, S., Strother, S. C., Arnott, S. R., … & Team, C. B. I. (2021). Accelerated brain aging in major depressive disorder and antidepressant treatment response: A CAN-BIND report. NeuroImage: Clinical, 32, 102864.
Caspani, G., Turecki, G., Lam, R. W., Milev, R. V., Frey, B. N., MacQueen, G. M., … & Swann, J. R. (2021). Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report. Communications Biology, 4(1), 1-11.
Cunningham, S., Mazurka, R., Wynne-Edwards, K. E., Milev, R. V., Pizzagalli, D. A., Kennedy, S., & Harkness, K. L. (2021). Cortisol reactivity to stress predicts behavioral responsivity to reward moderation by sex, depression, and anhedonia. Journal of Affective Disorders, 293, 1-8.
Davis, A. D., Hassel, S., Arnott, S. R., Hall, G. B., Harris, J. K., Zamyadi, M., … & Strother, S. C. (2022). Biophysical compartment models for single-shell diffusion MRI in the human brain: a model fitting comparison. Physics in Medicine & Biology, 67(5), 055009.
Kayvanrad, A., Arnott, S. R., Churchill, N., Hassel, S., Chemparathy, A., Dong, F., … & Strother, S. (2021). Resting state fMRI scanner instabilities revealed by longitudinal phantom scans in a multi-center study. NeuroImage, 237, 118197.
Liang, S., Beaton, D., Arnott, S. R., Gee, T., Zamyadi, M., Bartha, R., … & ONDRI Investigators. (2021). Magnetic Resonance Imaging Sequence Identification Using a Metadata Learning Approach. Frontiers in Neuroinformatics, 15.
Morton, E., Bhat, V., Giacobbe, P., Lou, W., Michalak, E. E., Chakrabarty, T., … & Lam, R. W. (2021). Impacts on quality of life with escitalopram monotherapy and aripiprazole augmentation in patients with major depressive disorder: a CAN-BIND report. Pharmacopsychiatry.
Morton, E., Bhat, V., Giacobbe, P., Lou, W., Michalak, E. E., McInerney, S., … & Lam, R. W. (2021). Predictors of Quality of Life Improvement with Escitalopram and Adjunctive Aripiprazole in Patients with Major Depressive Disorder: A CAN-BIND Study Report. CNS drugs, 35(4), 439-450.
Nunez, J. J., Nguyen, T. T., Zhou, Y., Cao, B., Ng, R. T., Chen, J., … & Lam, R. W. (2021). Replication of machine learning methods to predict treatment outcome with antidepressant medications in patients with major depressive disorder from STAR* D and CAN-BIND-1. PloS one, 16(6), e0253023.
Rnic, K., Jung, Y. E., Torres, I., Chakrabarty, T., LeMoult, J., Vaccarino, A. L., … & Team, C. B. I. (2021). Association between discrepancy in objective and subjective cognitive abilities and treatment response in patients with major depressive disorder: A CAN-BIND-1 study report. Journal of Affective Disorders, 295, 1095-1101.
Saeedi, S., Nagy, C., Ibrahim, P., Theroux, J. F., Wakid, M., Fiori, L., … & Turecki, G. (2021). Neuron-derived extracellular vesicles extracted from plasma show altered size and miRNA cargo as a function of antidepressant drug response. bioRxiv.
Shakeel, M. K., MacQueen, G., Addington, J., Metzak, P. D., Georgopoulos, G., Bray, S., … & Lebel, C. (2020). White Matter Connectivity in Youth at Risk for Serious Mental Illness: A Longitudinal Analysis. Psychiatry Research: Neuroimaging, 302, 111106.
Suh, J. S., Fiori, L. M., Ali, M., Harkness, K. L., Ramonas, M., Minuzzi, L., … & Frey, B. N. (2021). Hypothalamus volume and DNA methylation of stress axis genes in major depressive disorder: A CAN-BIND study report. Psychoneuroendocrinology, 132, 105348.
Theyers, A. E., Zamyadi, M., O’Reilly, M., Bartha, R., Symons, S., MacQueen, G. M., … & Arnott, S. R. (2021). Multisite Comparison of MRI Defacing Software Across Multiple Cohorts. Frontiers in psychiatry, 12, 189.
van der Wijk, G., Harris, J. K., Hassel, S., Davis, A. D., Zamyadi, M., Arnott, S. R., … & Protzner, A. B. (2021). Baseline functional connectivity in resting state networks associated with depression and remission status after 16 weeks of pharmacotherapy: A CAN-BIND Report. medRxiv.
Yrondi, A., Fiori, L. M., Nogovitsyn, N., Hassel, S., Théroux, J. F., Aouabed, Z., … & Turecki, G. (2021). Association between the expression of lncRNA BASP-AS1 and volume of right hippocampal tail moderated by episode duration in major depressive disorder: a CAN-BIND 1 report. Translational psychiatry, 11(1), 1-7.
- 2020
Alders, G. L., Davis, A. D., MacQueen, G., Strother, S. C., Hassel, S., Zamyadi, M., Sharma, G. B., Arnott, S. R., Downar, J., Harris, J. K., Lam, R. W., Milev, R., Müller, D. J., Ravindran, A., Kennedy, S. H., Frey, B. N., Minuzzi, L., & Hall, G. B. (2020). Escitalopram ameliorates differences in neural activity between healthy comparison and major depressive disorder groups on an fMRI emotional conflict task: A CAN-BIND-1 study. Journal of Affective Disorders, 264, 414-424. https://doi.org/10.1016/j.jad.2019.11.068
Belzeaux, R., Gorgievski, V., Fiori, L. M., Lopez, J. P., Grenier, J., Lin, R., Nagy, C., Ibrahim, E. C., Gascon, E., Courtet, P., Richard-Devantoy, S., Berlim, M., Chachamovich, E., Théroux, J., Dumas, S., Giros, B., Rotzinger, S., Soares, C. N., Foster, J. A., … Turecki, G. (2020). GPR56/ADGRG1 is associated with response to antidepressant treatment. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-15423-5
Daniels, S., Horman, T., Lapointe, T., Melanson, B., Storace, A., Kennedy, S. H., Frey, B. N., Rizvi, S. J., Hassel, S., Mueller, D. J., Parikh, S. V., Lam, R. W., Blier, P., Farzan, F., Giacobbe, P., Milev, R., Placenza, F., Soares, C. N., Turecki, G., … Leri, F. (2020). Reverse translation of major depressive disorder symptoms: A framework for the behavioural phenotyping of putative biomarkers. Journal of Affective Disorders, 263, 353-366. https://doi.org/10.1016/j.jad.2019.11.108
Dunlop, K., Rizvi, S. J., Kennedy, S. H., Hassel, S., Strother, S. C., Harris, J. K., Zamyadi, M., Arnott, S. R., Davis, A. D., Mansouri, F., Schulze, L., Ceniti, A. K., Lam, R. W., Milev, R., Rotzinger, S., Foster, J. A., Frey, B. N., Parikh, S. V., Soares, C. N., … Downar, J. (2020). Clinical, behavioral, and neural measures of reward processing correlate with escitalopram response in depression: A Canadian biomarker integration network in depression (CAN-BIND-1) report. Neuropsychopharmacology, 45(8), 1390-1397. https://doi.org/10.1038/s41386-020-0688-x
Hassel, S., Sharma, G. B., Alders, G. L., Davis, A. D., Arnott, S. R., Frey, B. N., Hall, G. B., Harris, J. K., Lam, R. W., Milev, R., Müller, D. J., Rotzinger, S., Zamyadi, M., Kennedy, S. H., Strother, S. C., & MacQueen, G. M. (2020). Reliability of a functional magnetic resonance imaging task of emotional conflict in healthy participants. Human Brain Mapping, 41(6), 1400-1415. https://doi.org/10.1002/hbm.24883
Horman, T., Fernandes, M. F., Tache, M. C., Hucik, B., Mutch, D. M., & Leri, F. (2020). Dietary N-6/N-3 ratio influences brain fatty acid composition in adult rats. Nutrients, 12(6), 1847. https://doi.org/10.3390/nu12061847
Marshe, V. S., Islam, F., Maciukiewicz, M., Fiori, L. M., Yerko, V., Yang, J., Turecki, G., Foster, J. A., Kennedy, S. H., Blumberger, D. M., Karp, J. F., Kennedy, J. L., Mulsant, B. H., Reynolds, C. F., Lenze, E. J., & Müller, D. J. (2020). Validation study of microRNAs previously associated with antidepressant response in older adults treated for late-life depression with venlafaxine. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 100, 109867. https://doi.org/10.1016/j.pnpbp.2020.109867
Nogovitsyn, N., Addington, J., Souza, R., Placsko, T. J., Stowkowy, J., Wang, J., Goldstein, B. I., Bray, S., Lebel, C., Taylor, V. H., Kennedy, S. H., & MacQueen, G. (2020). Childhood trauma and amygdala nuclei volumes in youth at risk for mental illness. Psychological Medicine, 1-8. https://doi.org/10.1017/s0033291720003177
Nogovitsyn, N., Souza, R., Muller, M., Srajer, A., Metzak, P. D., Hassel, S., Ismail, Z., Protzner, A., Bray, S. L., Lebel, C., MacIntosh, B. J., Goldstein, B. I., Wang, J., Kennedy, S. H., Addington, J., & MacQueen, G. M. (2020). Aberrant limbic brain structures in young individuals at risk for mental illness. Psychiatry and Clinical Neurosciences, 74(5), 294-302. https://doi.org/10.1111/pcn.12985
Phillips, J. L., Jaworska, N., Kamler, E., Bhat, V., Blier, J., Foster, J. A., Hassel, S., Ho, K., McMurray, L., Milev, R., Moazamigoudarzi, Z., Placenza, F. M., Richard-Devantoy, S., Rotzinger, S., Turecki, G., Vazquez, G. H., Kennedy, S. H., & Blier, P. (2020). A randomized, crossover comparison of ketamine and electroconvulsive therapy for treatment of major depressive episodes: A Canadian biomarker integration network in depression (CAN-BIND) study protocol. BMC Psychiatry, 20(1). https://doi.org/10.1186/s12888-020-02672-3
Suh, J. S., Minuzzi, L., Raamana, P. R., Davis, A., Hall, G. B., Harris, J., Hassel, S., Zamyadi, M., Arnott, S. R., Alders, G. L., Sassi, R. B., Milev, R., Lam, R. W., MacQueen, G. M., Strother, S. C., Kennedy, S. H., & Frey, B. N. (2020). An investigation of cortical thickness and antidepressant response in major depressive disorder: A CAN-BIND study report. NeuroImage: Clinical, 25, 102178. https://doi.org/10.1016/j.nicl.2020.102178
Uher, R., Frey, B. N., Quilty, L. C., Rotzinger, S., Blier, P., Foster, J. A., Müller, D. J., Ravindran, A. V., Soares, C. N., Turecki, G., Parikh, S. V., Milev, R., MacQueen, G., Lam, R. W., & Kennedy, S. H. (2020). Symptom dimension of interest-activity indicates need for aripiprazole augmentation of Escitalopram in major depressive disorder. The Journal of Clinical Psychiatry, 81(4). https://doi.org/10.4088/jcp.20m13229
Vallati, M., Cunningham, S., Mazurka, R., Stewart, J. G., Larocque, C., Milev, R. V., Bagby, R. M., Kennedy, S. H., & Harkness, K. L. (2020). Childhood maltreatment and the clinical characteristics of major depressive disorder in adolescence and adulthood. Journal of Abnormal Psychology, 129(5), 469-479. https://doi.org/10.1037/abn0000521
Zhdanov, A., Atluri, S., Wong, W., Vaghei, Y., Daskalakis, Z. J., Blumberger, D. M., Frey, B. N., Giacobbe, P., Lam, R. W., Milev, R., Mueller, D. J., Turecki, G., Parikh, S. V., Rotzinger, S., Soares, C. N., Brenner, C. A., Vila-Rodriguez, F., McAndrews, M. P., Kleffner, K., … Farzan, F. (2020). Use of machine learning for predicting Escitalopram treatment outcome from electroencephalography recordings in adult patients with depression. JAMA Network Open, 3(1), e1918377. https://doi.org/10.1001/jamanetworkopen.2019.18377
- 2019
Alders, G. L., Davis, A. D., MacQueen, G., Strother, S. C., Hassel, S., Zamyadi, M., … Hall, G. B. (2019). Reduced accuracy accompanied by reduced neural activity during the performance of an emotional conflict task by unmedicated patients with major depression: A CAN-BIND fMRI study. Journal of Affective Disorders, 257(June), 765–773. https://doi.org/10.1016/j.jad.2019.07.037
Allen, T. A., Lam, R. W., Milev, R., Rizvi, S. J., Frey, B. N., MacQueen, G. M., … Quilty, L. C. (2019). Early change in reward and punishment sensitivity as a predictor of response to antidepressant treatment for major depressive disorder: A CAN-BIND-1 report. Psychological Medicine, 49(10), 1629–1638. https://doi.org/10.1017/S0033291718002441
Belzeaux, R., Fiori, L. M., Lopez, J. P., Boucekine, M., Boyer, L., Blier, P., … Turecki, G. (2019). Predicting Worsening Suicidal Ideation With Clinical Features and Peripheral Expression of Messenger RNA and MicroRNA During Antidepressant Treatment. Journal of Clinical Psychiatry.
Chakrabarty, T., Harkness, K. L., McInerney, S. J., Quilty, L. C., Milev, R. V., Kennedy, S. H., … Lam, R. W. (2019). Childhood maltreatment and cognitive functioning in patients with major depressive disorder: a CAN-BIND-1 report. Psychological Medicine. https://doi.org/10.1017/s003329171900268x
Davis, A. D., Hassel, S., Arnott, S. R., Harris, J., Lam, R. W., Milev, R., … Hall, G. B. (2019). White Matter Indices of Medication Response in Major Depression: A Diffusion Tensor Imaging Study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, (Md), 1–12. https://doi.org/10.1016/j.bpsc.2019.05.016
Fonseka, T. M., Pong, J. T., Kcomt, A., Kennedy, S. H., & Parikh, S. V. (2019). Collaborating with individuals with lived experience to adapt CANMAT clinical depression guidelines into a patient treatment guide: The CHOICE‐D co‐design process. Journal of evaluation in clinical practice.
Janzen, T. B., Al Shirawi, M. I., Rotzinger, S., Kennedy, S. H., & Bartel, L. (2019). A pilot study investigating the effect of music-based intervention on depression and anhedonia. Frontiers in Psychology, 10(MAY), 1–13. https://doi.org/10.3389/fpsyg.2019.01038
Ju, C., Fiori, L. M., Belzeaux, R., Theroux, J.-F., Chen, G. G., Aouabed, Z., … Turecki, G. (2019). Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants. Translational Psychiatry, 9(1). https://doi.org/10.1038/s41398-019-0589-0
Kim, H. K., Tyryshkin, K., Elmi, N., Dharsee, M., Evans, K. R., Good, J., … Feilotter, H. (2019). Plasma microRNA expression levels and their targeted pathways in patients with major depressive disorder who are responsive to duloxetine treatment. Journal of Psychiatric Research, 110(December 2018), 38–44. https://doi.org/10.1016/j.jpsychires.2018.12.007
MacQueen, G. M., Hassel, S., Arnott, S. R., Addington, J., Bowie, C. R., Bray, S. L., … Kennedy, S. H. (2019). The Canadian Biomarker Integration Network in Depression (CAN-BIND): magnetic resonance imaging protocols. Journal of Psychiatry and Neuroscience, 44(4), 223–236. https://doi.org/10.1503/jpn.180036
McInerney, S. J., Fallahi, A., Edgar, N. E., Ceniti, A. K., Rizvi, S. J., Beder, M., … & Kennedy, S. H. (2019). Suicide-related presentations of homeless individuals to an inner-city emergency department. General hospital psychiatry.
Nogovitsyn, N., Muller, M., Souza, R., Hassel, S., Arnott, S. R., Davis, A. D., Hall, G. B., Harris, J. K., Zamyadi, M., Metzak, P. D., Ismail, Z., Downar, J., Parikh, S. V., Soares, C. N., Addington, J. M., Milev, R., Harkness, K. L., Frey, B. N., Lam, R. W., … MacQueen, G. M. (2019). Hippocampal tail volume as a predictive biomarker of antidepressant treatment outcomes in patients with major depressive disorder: A CAN-BIND report. Neuropsychopharmacology, 45(2), 283-291. https://doi.org/10.1038/s41386-019-0542-1
Nogovitsyn, N., Souza, R., Muller, M., Srajer, A., Hassel, S., Arnott, S. R., … MacQueen, G. M. (2019). Testing a deep convolutional neural network for automated hippocampus segmentation in a longitudinal sample of healthy participants. NeuroImage, 197(March), 589–597. https://doi.org/10.1016/j.neuroimage.2019.05.017
Sidney H. Kennedy, Raymond W. Lam, Susan Rotzinger, Roumen V. Milev, Pierre Blier, Jonathan Downar, Kenneth R. Evans, Faranak Farzan, Jane A. Foster, Benicio N. Frey, Peter Giacobbe, Geoffrey B. Hall, Kate L. Harkness, Stefanie Hassel, Zahinoor Ismail, Fr, and R. U. (2019). Symptomatic and Functional Outcomes and Early Prediction of Response to Escitalopram Monotherapy and Sequential Adjunctive Aripiprazole Therapy in Patients With Major Depressive Disorder: A CAN-BIND-1 Report. Journal of Clinical Psychiatry, 80(2), 11–12. Retrieved from 10.4088/JCP.18m12202
Storace A, Daniels S, Zhou Y, Kalisch B, Parker L, Rock E, Limebeer C, Lapointe T, Leri F (2019). A study of limbic brain derived neurotrophic factor gene expression in male Sprague-Dawley rats trained on a learned helplessness task. Behav Brain Res 30: 376.
Yrondi, A., Fiori, L. M., Frey, B. N., Lam, R. W., MacQueen, G. M., Milev, R., Müller, D. J., Foster, J. A., Kennedy, S. H., & Turecki, G. (2020). Association between side effects and blood microrna expression levels and their targeted pathways in patients with major depressive disorder treated by a selective serotonin reuptake inhibitor, escitalopram: A CAN-BIND-1 report. International Journal of Neuropsychopharmacology, 23(2), 88–95. https://doi.org/10.1093/ijnp/pyz066
- 2018
Allega, O. R., Leng, X., Vaccarino, A., Skelly, M., Lanzini, M., Paz Hidalgo, M., … Frey, B. N. (2018). Performance of the biological rhythms interview for assessment in neuropsychiatry: An item response theory and actigraphy analysis. Journal of Affective Disorders, 225(June 2017), 54–63. https://doi.org/10.1016/j.jad.2017.07.047
Allen, T. A., Carey, B. E., McBride, C., Bagby, R. M., DeYoung, C. G., & Quilty, L. C. (2018). Big Five aspects of personality interact to predict depression. Journal of Personality, 86(4), 714–725. https://doi.org/10.1111/jopy.12352
Fonseka, T. M., MacQueen, G. M., & Kennedy, S. H. (2018). Neuroimaging biomarkers as predictors of treatment outcome in Major Depressive Disorder. Journal of Affective Disorders, 233(October 2017), 21–35. https://doi.org/10.1016/j.jad.2017.10.049
Maciukiewicz, M., Marshe, V. S., Tiwari, A. K., Fonseka, T. M., Freeman, N., Kennedy, J. L., … Müller, D. J. (2018). Genome-wide association studies of placebo and duloxetine response in major depressive disorder. Pharmacogenomics Journal, 18(3), 406–412. https://doi.org/10.1038/tpj.2017.29
Maciukiewicz, Malgorzata, Marshe, V. S., Hauschild, A. C., Foster, J. A., Rotzinger, S., Kennedy, J. L., … Geraci, J. (2018). GWAS-based machine learning approach to predict duloxetine response in major depressive disorder. Journal of Psychiatric Research, 99(June 2017), 62–68. https://doi.org/10.1016/j.jpsychires.2017.12.009
Rizvi, S. J., Lambert, C., & Kennedy, S. (2018). Presentation and Neurobiology of Anhedonia in Mood Disorders: Commonalities and Distinctions. Current Psychiatry Reports, 20(2), 6–9. https://doi.org/10.1007/s11920-018-0877-z
- 2017
Al Shirawi, M. I., Kennedy, S. H., Ho, K. T., Byrne, R., & Downar, J. (2017). Oral Ketamine in Treatment-Resistant Depression. Journal of Clinical Psychopharmacology, 37(4), 464–467. https://doi.org/10.1097/JCP.0000000000000717
Baskaran, A., Farzan, F., Milev, R., Brenner, C. A., Alturi, S., Pat McAndrews, M., … Kennedy, S. H. (2017). The comparative effectiveness of electroencephalographic indices in predicting response to escitalopram therapy in depression: A pilot study. Journal of Affective Disorders, 227(September 2017), 542–549. https://doi.org/10.1016/j.jad.2017.10.028
Farzan, F., Atluri, S., Frehlich, M., Dhami, P., Kleffner, K., Price, R., … Kennedy, S. H. (2017). Standardization of electroencephalography for multi-site, multi-platform and multi-investigator studies: Insights from the Canadian Biomarker Integration Network in Depression. Scientific Reports, 7(1), 1–11. https://doi.org/10.1038/s41598-017-07613-x
Fiori, L. M., Lopez, J. P., Richard-Devantoy, S., Berlim, M., Chachamovich, E., Jollant, F., … Turecki, G. (2017). Investigation of miR-1202, miR-135a, and miR-16 in Major Depressive Disorder and Antidepressant Response. International Journal of Neuropsychopharmacology, 20(8), 619–623. https://doi.org/10.1093/ijnp/pyx034
Lopez, J. P., Fiori, L. M., Cruceanu, C., Lin, R., Labonte, B., Cates, H. M., … Turecki, G. (2017). MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes. Nature Communications, 8(May), 1–12. https://doi.org/10.1038/ncomms15497
- 2016
Fonseka, T. M., Wen, X. Y., Foster, J. A., & Kennedy, S. H. (2016). Zebrafish models of major depressive disorders. Journal of Neuroscience Research, 94(1), 3–14. https://doi.org/10.1002/jnr.23639
Lam, R. W., Milev, R., Rotzinger, S., Andreazza, A. C., Blier, P., Brenner, C., … Kennedy, S. H. (2016). Discovering biomarkers for antidepressant response: Protocol from the Canadian Biomarker Integration Network in Depression (CAN-BIND) and clinical characteristics of the first patient cohort. BMC Psychiatry, 16(1), 1–13. https://doi.org/10.1186/s12888-016-0785-x
Vaccarino, A. L., Evans, K. R., Kalali, A. H., Kennedy, S. H., Engelhardt, N., Frey, B. N., … Williams, J. B. W. (2016). The depression inventory development workgroup: A collaborative, empirically driven initiative to develop a new assessment tool for major depressive disorder. Innovations in Clinical Neuroscience, 13(9–10), 20–31.
- 2015
Genetic variation in IL-1β, IL-2, IL-6, TSPO and BDNF and response to duloxetine or placebo treatment in major depressive disorder
Maciukiewicz M, et al. (2015). Genetic variation in IL-1beta, IL-2, IL-6, TSPO and BDNF and response to duloxetine or placebo treatment in major depressive disorder. Pharmacogenomics, 16(17):1919-1929.Zebrafish models of major depressive disorders
Fonseka, T. M., Wen, X., Foster, J. A., & Kennedy, S.H. (2015). Zebrafish models of major depressive disorders. Journal of Neuroscience Research, 94(1), 3-14. doi:10.1002/jnr.23639Fructose: Glucose Ratios—A Study of Sugar Self-Administration and Associated Neural and Physiological Responses in the Rat
Levy, A., Marshall, P., Zhou, Y., Kreek, M., Kent, K., Daniels, S., Shore, A., Downs, T., Fernandes, M.F., Mutch, D.M., Leri, F. (2015). Fructose:Glucose Ratios—A Study of Sugar Self-Administration and Associated Neural and Physiological Responses in the Rat. Nutrients, 7(5), 3869-3890. doi:10.3390/nu7053869- 2014 and prior
Restoration of serotonin neuronal firing following long-term administration of bupropion but not paroxetine in olfactory bulbectomized rats
El Mansari, M., Manta, S., Oosterhof, C., Iskandrani, K. S., Chenu, F., Shim, S., & Blier, P. (2014). Restoration of Serotonin Neuronal Firing Following Long-Term Administration of Bupropion but Not Paroxetine in Olfactory Bulbectomized Rats. International Journal of Neuropsychopharmacology, 18(4). doi:10.1093/ijnp/pyu050A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration
Levy, A., Limebeer, C. L., Ferdinand, J., Shillingford, U., Parker, L. A., & Leri, F. (2014). A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration. Journal of Visualized Experiments, (84). doi:10.3791/50956The Canadian Biomarker Integration Network in Depression (CAN-BIND): advances in response prediction
Kennedy, S. H., Downar, J., Evans, K. R., Feilotter, H., Lam, R. W., Macqueen, G. M., Milev, R., Parikh, S.V., Rotzinger, S. Soares, C. (2012). The Canadian Biomarker Integration Network in Depression (CAN-BIND): Advances in Response Prediction. Current Pharmaceutical Design, 18(36), 5976-5989. doi:10.2174/138161212803523635